Randomized Trials Analyzed as Observational Studies
نویسندگان
چکیده
منابع مشابه
Observational studies are complementary to randomized controlled trials.
Randomized controlled trials (RCTs) are considered the gold standard study design to investigate the effect of health interventions, including treatment. However, in some situations, it may be unnecessary, inappropriate, impossible, or inadequate to perform an RCT. In these special situations, well-designed observational studies, including cohort and case-control studies, may provide an alterna...
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The term observational study describes a wide range of study designs including prospective and retrospective cohort studies, case-control studies, and cross-sectional studies, a defining feature of which is that any intervention studied is determined by clinical practice and not the protocol. Data from large, prospective observational studies provide information about the safety and efficacy of...
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ژورنال
عنوان ژورنال: Annals of Internal Medicine
سال: 2013
ISSN: 0003-4819
DOI: 10.7326/0003-4819-159-8-201310150-00709